Binary Fission :
(i) Nucleus divides into two parts. (ii) It occurs during normal conditions. (iii) It gives rise to two individuals. (iv) Cytoplasm divides after each nuclear division. (v) Includes definite pattern of division.
e.g., Amoeba.
Multiple Fission : (i) Nucleus divides into many parts. (ii) It takes place during unfavourable conditions (Encysted stage), (iii) It forms many individuals. (iv) Cytoplasm does not divide after every nuciear division. (v) Has no definite pattern of division.
e.g., Plasmodium.